2-Phenylquinoline

2-Phenylquinoline

SCHEMBL44999

c1ccc(-c2ccc3ccccc3n2)cc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 14/20 0.73
NPC1 O15118 12/20 0.73
AR P10275 2/20 0.73
CYP3A4 P08684 2/20 0.73
CYP1A2 P05177 1/20 0.73
CYP2D6 P10635 1/20 0.73
CYP2C9 P11712 1/20 0.73
CYP2C19 P33261 1/20 0.73
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
KDM4E B2RXH2 8/20 0.68
SMN1; SMN2 Q16637 7/20 0.68
ALDH1A1 P00352 7/20 0.68
MAPT P10636 5/20 0.68
HSD17B10 Q99714 4/20 0.68
TP53 P04637 3/20 0.68
PKM P14618 3/20 0.68
HPGD P15428 3/20 0.68
GMNN O75496 1/20 0.68
THPO P40225 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylquinoline SCHEMBL29399739 1.00 RAB9A (0.73) RAB9ANPC1ARCYP3A4CYP1A2
2-Phenylquinoline SCHEMBL29498037 0.98 RAB9A (0.70) RAB9ANPC1ARCYP3A4CYP1A2
2-Phenylquinoline SCHEMBL28871326 0.98 RAB9A (0.70) RAB9ANPC1ARCYP3A4CYP1A2
2-Phenylquinoline SCHEMBL28983 0.98 RAB9A (0.70) RAB9ANPC1ARCYP3A4CYP1A2
2-Phenylquinoline SCHEMBL1815021 0.98 RAB9A (0.70) RAB9ANPC1ARCYP3A4CYP1A2
2-Phenylquinoline SCHEMBL346742 0.98 RAB9A (0.70) RAB9ANPC1ARCYP3A4CYP1A2
2-Phenylquinoline SCHEMBL5733254 0.98 RAB9A (0.70) RAB9ANPC1ARCYP3A4CYP1A2
2-Phenylquinoline SCHEMBL6858671 0.98 RAB9A (0.70) RAB9ANPC1ARCYP3A4CYP1A2
2-Phenylquinoline SCHEMBL29986142 0.98 RAB9A (0.70) RAB9ANPC1ARCYP3A4CYP1A2
2-Phenylquinoline SCHEMBL668531 0.98 RAB9A (0.70) RAB9ANPC1ARCYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7374 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121226451-B Iridium metal complex fluorescent probe for detecting norfloxacin, molecularly imprinted modified iridium probe fluorescent sensor, and preparation method and application thereof 宁波大学 2026-05-15 CN claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
US-12162899-B2 Photochromic germole-fused diarylethenes and production thereof THE UNIVERSITY OF HONG KONG (CN) 2024-12-10 US claimed
CN-118904228-A System and method for synthesizing lignin-based quinoline derivatives through continuous flow 沈阳理工大学 2024-11-08 CN claimed
CN-118566303-A Preparation and application of single-atom catalyst enhanced cathode electrochemical luminescence sensor 青岛科技大学 2024-08-30 CN claimed
CN-118516087-A Environment-friendly cooling liquid capable of being used for charging pile 中国石油化工股份有限公司 2024-08-20 CN claimed
CN-114641554-B Method for improving electrochemiluminescence signal in bioassay 苏州安赛诊断技术有限公司 2024-06-28 CN claimed
WO-2024126392-A1 VECTORIZED NHC IRIDIUM(III) COMPLEXES AND USE THEREOF IN PHOTODYNAMIC THERAPY AND/OR DIAGNOSTIC CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2024-06-20 WO claimed
EP-4385995-A1 VECTORIZED NHC IRIDIUM(III) COMPLEXES AND USE THEREOF IN PHOTODYNAMIC THERAPY AND/OR DIAGNOSTIC Centre National de la Recherche Scientifique (FR) 2024-06-19 EP claimed
CN-114874196-B Method for photochemically preparing pyridine/quinoline derivative 南京先进生物材料与过程装备研究院有限公司 2024-06-11 CN claimed
EP-0656790-A1 COMPOSITIONS AND METHODS FOR MODULATING RNA ISIS PHARMACEUTICALS, INC. (US) 1995-06-14 EP claimed
US-5334642-A Includes organic compound which has a base constant within the range 2 to 12 and boiling point higher than 300 degrees BASF AKTIENGESELLSCHAFT (DE) 1994-08-02 US claimed
WO-1993017717-A1 COMPOSITIONS AND METHODS FOR MODULATING RNA ISIS PHARMACEUTICALS, INC. (US) 1993-09-16 WO claimed
US-5208278-A STABILIZED POLYARYL ETHER KETONE MOLDING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1993-05-04 US claimed
EP-0451556-A2 Stabilised polyaryletherketone - moulding compounds BASF Aktiengesellschaft (DE) 1991-10-16 EP claimed
EP-0124875-B1 BATTERY HAVING AN ELECTRODE MADE OF A POLYMERIC COMPOUND WITH CONJUGATED DOUBLE BONDS SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-04-10 EP claimed
CN-85106626-A The preparation of 4-amino-2-phenyl-quinoline 1987-03-25 CN claimed
US-4619861-A COATING PARTICLES WITH ORGANONITROGEN OR ORGANOSULFUR POLYMER TDK CORPORATION (JP) 1986-10-28 US claimed
US-4544615-A POLYACETYLENE, POLYPYRROLES, AROMATIC RESINS SHOWA DENKO KABUSHIKI KAISHA (JP) 1985-10-01 US claimed
EP-0124875-A1 Battery having an electrode made of a polymeric compound with conjugated double bonds SHOWA DENKO KABUSHIKI KAISHA (JP) 1984-11-14 EP claimed