Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 8/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.69 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.69 |
| ▸ | CTSB | P07858 | 1/20 | 0.69 |
| ▸ | ELANE | P08246 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 4/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5390639 | 0.88 | ALDH1A1 (0.73) | AKT1MEN1KMT2AKLKB1CTSB | |
| SCHEMBL287025 | 0.83 | AKT1 (1.00) | AKT1MEN1KMT2AKLKB1CTSB | |
| SCHEMBL282800 | 0.83 | AKT1 (0.82) | AKT1MEN1KMT2AKLKB1CTSB | |
| SCHEMBL3468247 | 0.82 | ALDH1A1 (0.66) | AKT1MEN1KMT2AKLKB1CTSB | |
| SCHEMBL5393345 | 0.82 | ALDH1A1 (0.66) | AKT1MEN1KMT2AKLKB1CTSB | |
| SCHEMBL3466806 | 0.81 | ALDH1A1 (0.66) | AKT1MEN1KMT2AKLKB1CTSB | |
| SCHEMBL5407138 | 0.81 | MEN1 (1.00) | AKT1MEN1KMT2AKLKB1CTSB | |
| SCHEMBL282833 | 0.81 | AKT1 (0.78) | AKT1MEN1KMT2AKLKB1CTSB | |
| SCHEMBL11891683 | 0.80 | AKT1 (0.77) | AKT1MEN1KMT2AKLKB1CTSB | |
| SCHEMBL10108459 | 0.80 | AKT1 (0.80) | AKT1MEN1KMT2AKLKB1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |