Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | GGT1 | P19440 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467388 | 0.86 | ALDH1A1 (0.69) | ALDH1A1GGT1MEN1KMT2AMAPT | |
| SCHEMBL3468536 | 0.82 | ALDH1A1 (0.55) | ALDH1A1GGT1MEN1KMT2AMAPT | |
| SCHEMBL3467954 | 0.82 | ALDH1A1 (0.57) | ALDH1A1GGT1MEN1KMT2AMAPT | |
| SCHEMBL3467627 | 0.75 | ALDH1A1 (0.54) | ALDH1A1GGT1MEN1KMT2AMAPT | |
| SCHEMBL3467279 | 0.73 | P2RY1 (0.54) | ALDH1A1GGT1MEN1KMT2AMAPT | |
| SCHEMBL3467937 | 0.73 | ALDH1A1 (0.52) | ALDH1A1GGT1MEN1KMT2AMAPT | |
| SCHEMBL3467123 | 0.72 | MEN1 (0.47) | ALDH1A1GGT1MEN1KMT2AMAPT | |
| SCHEMBL3011618 | 0.70 | ALDH1A1 (1.00) | ALDH1A1GGT1MEN1KMT2AMAPT | |
| SCHEMBL14864422 | 0.67 | ATM (1.00) | ALDH1A1GGT1MEN1KMT2APKM | |
| SCHEMBL3467488 | 0.67 | ALDH1A1 (0.79) | ALDH1A1GGT1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |