Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GLS | O94925 | 2/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467954 | 0.91 | ALDH1A1 (0.57) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3467186 | 0.82 | ATM (0.52) | ALDH1A1PKMMEN1KMT2AGGT1 | |
| SCHEMBL3467388 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3468536 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3466966 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3467359 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3467627 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2AGLS | |
| SCHEMBL3467524 | 0.73 | P2RY1 (0.44) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3467571 | 0.73 | ALDH1A1 (0.54) | ALDH1A1MAPTPKMMEN1KMT2A | |
| SCHEMBL3468791 | 0.72 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2AGGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |