Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467235 | 0.83 | ALDH1A1 (0.49) | LMNAHSD17B10ALDH1A1CCR2MEN1 | |
| SCHEMBL3467524 | 0.83 | P2RY1 (0.44) | PKMHSD17B10ALDH1A1CCR2MEN1 | |
| SCHEMBL3466833 | 0.82 | ALDH1A1 (0.54) | LMNAPKMHSD17B10ALDH1A1MEN1 | |
| SCHEMBL3467620 | 0.79 | MEN1 (0.40) | CCR2MEN1KMT2AP2RY1KDM1A | |
| SCHEMBL3478056 | 0.78 | ALDH1A1 (0.52) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL3467036 | 0.77 | MEN1 (0.53) | PKMHSD17B10ALDH1A1FFAR1CCR2 | |
| SCHEMBL3468245 | 0.76 | ALDH1A1 (0.52) | LMNAPKMHSD17B10ALDH1A1MEN1 | |
| SCHEMBL3467495 | 0.74 | ALDH1A1 (0.49) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL5389518 | 0.73 | MEN1 (0.74) | LMNAPKMHSD17B10ALDH1A1CCR2 | |
| SCHEMBL3467458 | 0.73 | ALDH1A1 (0.61) | LMNAHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |