Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467354 | 0.90 | ALDH1A1 (0.61) | ALDH1A1MAPTSCN1ASCN8AMEN1 | |
| SCHEMBL3467235 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2AGGT1 | |
| SCHEMBL3468791 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2AGGT1 | |
| SCHEMBL3467885 | 0.78 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2AGGT1 | |
| SCHEMBL3478056 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1KMT2AGGT1 | |
| SCHEMBL3467186 | 0.75 | ATM (0.52) | ALDH1A1MEN1KMT2AGGT1SMN1; SMN2 | |
| SCHEMBL3467933 | 0.74 | KCNJ5 (0.38) | MAPTSCN1ASCN8AMEN1KMT2A | |
| SCHEMBL3468816 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2AGGT1 | |
| SCHEMBL3467609 | 0.74 | LMNA (0.53) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3467524 | 0.73 | P2RY1 (0.44) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |