Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 3/20 | 0.57 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.48 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.48 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.48 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.48 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.48 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.48 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.48 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.48 |
| ▸ | CTSC | P53634 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
| ▸ | BCR | P11274 | 4/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466346 | 0.88 | TTK (0.45) | TTKATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5403304 | 0.84 | FLT3 (0.50) | TTKATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL12409302 | 0.81 | TTK (0.66) | TTKSRCAURKAAURKBMAPKAPK5 | |
| SCHEMBL3466981 | 0.81 | SRC (0.56) | TTKSRCTP53SMN1; SMN2AURKA | |
| SCHEMBL3469745 | 0.80 | ABL1 (0.51) | TTKABL1BCRAURKAAURKB | |
| SCHEMBL3466944 | 0.79 | DYRK1A (0.44) | TTKCTSCDHODHABL1BCR | |
| SCHEMBL3469554 | 0.78 | TTK (0.64) | TTKATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL3469478 | 0.78 | ABL1 (0.44) | TTKCTSCABL1BCREPHX2 | |
| SCHEMBL3466296 | 0.77 | POLB (0.48) | TTKSRCABL1BCR | |
| SCHEMBL30138985 | 0.77 | MAPKAPK5 (0.62) | TTKSRCAURKAAURKBMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |