SCHEMBL3467994

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3468543	0.90	ESR1 (0.42)	ESR1GABRPGABRDGABRA1GABRB1
	SCHEMBL3468463	0.85	ESR1 (0.42)	ESR1GABRPGABRDGABRA1GABRB1
	SCHEMBL3468051	0.83	GABRP (0.43)	ESR1GABRPGABRDGABRA1GABRB1
	SCHEMBL3468408	0.80	ESR1 (0.56)	ESR1LMNAMEN1KMT2A
	SCHEMBL3469083	0.79	ESR1 (0.42)	ESR1
	SCHEMBL3469066	0.78	CA2 (0.48)	ESR1GRIN2BPOLBKMT2A
	SCHEMBL3468125	0.78	ESR1 (0.46)	ESR1
	SCHEMBL3469351	0.78	ESR1 (0.41)	ESR1POLBLMNAMEN1KMT2A
	SCHEMBL3469363	0.78	ESR1 (0.47)	ESR1GABRPGABRDGABRA1GABRB1
	SCHEMBL3468111	0.77	CA2 (0.50)	ESR1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.