Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28322766 | 0.88 | TSHR (0.40) | TSHRTDP1MEN1KMT2A | |
| Alcohol SCHEMBL5066648 | 0.85 | TSHR (0.38) | TSHRTDP1MEN1KMT2A | |
| Methyl Alcohol SCHEMBL2652388 | 0.84 | MEN1 (0.38) | TSHRMEN1KMT2A | |
| SCHEMBL7097725 | 0.84 | — | — | |
| SCHEMBL5544690 | 0.84 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL1746 | 0.84 | — | — | |
| Isopropyl Alcohol SCHEMBL28105402 | 0.81 | ALDH1A1 (0.40) | TSHRTDP1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL1997314 | 0.81 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL319537 | 0.81 | MEN1 (0.40) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL22577541 | 0.81 | MEN1 (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222639-A1 | BIARYL PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS | Decode Genetics EHF (IS) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009067621-A1 | BIARYL PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |