Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28322766 | 0.97 | TSHR (0.40) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Water SCHEMBL1251556 | 0.90 | MEN1 (0.40) | MEN1KMT2A | |
| Methyl Alcohol SCHEMBL2652388 | 0.87 | MEN1 (0.38) | TSHRMEN1KMT2A | |
| SCHEMBL5544690 | 0.87 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL7097725 | 0.87 | — | — | |
| SCHEMBL1746 | 0.87 | — | — | |
| Hexane SCHEMBL7698301 | 0.86 | SMN1; SMN2 (0.41) | TSHRALDH1A1MEN1KMT2A | |
| Isobutanol SCHEMBL3468010 | 0.85 | TSHR (0.53) | TSHRMEN1KMT2ATDP1 | |
| Hydrazine SCHEMBL28180292 | 0.84 | MEN1 (0.36) | MEN1KMT2A | |
| Isopropyl Alcohol SCHEMBL28105402 | 0.84 | ALDH1A1 (0.40) | TSHRALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1759210-B1 | METHOD FOR PREPARING SUBSTRATES HAVING IMMOBILIZED MOLECULES AND SUBSTRATES | NANOSPHERE INC (US) | 2008-12-31 | — | — | EP | disclosed |
| US-20050287560-A1 | Method for preparing substrates having immobilized molecules and substrates | NANOSPHERE, INC. | 2005-12-29 | — | — | US | disclosed |