Isobutanol

Isobutanol

SCHEMBL3468012

CC(C)C(C)(N)C(C)C.CC(C)CO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL28625111 0.85 TSHR (0.38) TSHRTDP1
Methyl Alcohol SCHEMBL27508368 0.81 ALDH1A1 (0.35)
SCHEMBL1980 0.80
Isobutanol SCHEMBL11524818 0.79 TSHR (0.56) TSHRTDP1
Fluoride SCHEMBL73857 0.77
Hydrochloric Acid SCHEMBL366445 0.77
Iodide SCHEMBL115030 0.77
Fluoride SCHEMBL1025919 0.77
Ammonia Solution, Strong SCHEMBL4950713 0.77
Chloromethane SCHEMBL29210875 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2222639-A1 BIARYL PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS Decode Genetics EHF (IS) 2010-09-01 EP disclosed
WO-2009067621-A1 BIARYL PDE4 INHIBITORS FOR TREATING PULMONARY AND CARDIOVASCULAR DISORDERS DECODE GENETICS EHF (IS) 2009-05-28 WO disclosed