Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CLK1 | P49759 | 1/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12821680 | 0.81 | GSK3B (0.81) | GSK3BMAPTLMNARAB9APOLB | |
| SCHEMBL12821679 | 0.81 | GSK3B (0.81) | GSK3BMAPTLMNARAB9APOLB | |
| SCHEMBL10750983 | 0.80 | GSK3B (0.68) | GSK3BMAPTLMNARAB9APOLB | |
| SCHEMBL10750988 | 0.80 | GSK3B (0.68) | GSK3BMAPTLMNARAB9APOLB | |
| SCHEMBL15305605 | 0.78 | MEN1 (0.67) | GSK3BMAPTLMNARAB9APOLB | |
| SCHEMBL15421760 | 0.76 | GSK3B (0.67) | GSK3BMAPTLMNARAB9APOLB | |
| SCHEMBL10750025 | 0.76 | GSK3B (0.67) | GSK3BMAPTLMNARAB9APOLB | |
| SCHEMBL10750021 | 0.76 | GSK3B (0.67) | GSK3BMAPTLMNARAB9APOLB | |
| SCHEMBL3125849 | 0.76 | GSK3B (0.70) | GSK3BMAPTLMNARAB9APOLB | |
| SCHEMBL15421424 | 0.76 | GSK3B (0.70) | GSK3BMAPTLMNARAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170326045-A1 | COSMETIC COMPOSITION COMPRISING A SYNTHETIC PHYLLOSILICATE AND A POLYOL AND/OR A UV FILTER | L'OREAL (FR) | 2017-11-16 | — | — | US | disclosed |
| US-20170304658-A1 | GEL/GEL COMPOSITION COMPRISING A UV-SCREENING AGENT | L'OREAL (FR) | 2017-10-26 | — | — | US | disclosed |
| US-20150190320-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES | L'OREAL (FR) | 2015-07-09 | — | — | US | disclosed |
| US-20150157539-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES | L'OREAL (FR) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326045-A1 | COSMETIC COMPOSITION COMPRISING A SYNTHETIC PHYLLOSILICATE AND A POLYOL AND/OR A UV FILTER | PUF60, POLR1C, DPM1 | GSK3B 2412/4885MAPT 938/4885LMNA 2324/4885 |
| US-20150157539-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES | MITF, RAB5IF, TYR | GSK3B 4768/4885MAPT 922/4885LMNA 683/4885 |
| US-20170304658-A1 | GEL/GEL COMPOSITION COMPRISING A UV-SCREENING AGENT | CUTA, KRT18, APOL1 | GSK3B 4002/4885MAPT 369/4885LMNA 31/4885 |
| US-20150190320-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES | XPA, ERCC1, ERCC4 | GSK3B 4686/4885MAPT 2352/4885LMNA 942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.