SCHEMBL3468045

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13161214	0.85	DEGS1 (0.45)	ESR1
	SCHEMBL3468408	0.83	ESR1 (0.56)	ESR1MEN1NPC1RAB9AKMT2A
	SCHEMBL3468563	0.82	MMP3 (0.47)	ESR1MEN1NPC1RAB9AKMT2A
	SCHEMBL3468080	0.80	ESR1 (0.51)	ESR1MEN1RAB9AKMT2AHSD17B1
	SCHEMBL3469077	0.79	ESR1 (0.43)	ESR1MEN1NPC1RAB9AKMT2A
	SCHEMBL13161286	0.78	MMP3 (0.53)	ESR1SMN1; SMN2HSD17B1
	SCHEMBL3075044	0.77	ESR1 (0.50)	ESR1MEN1RAB9AKMT2ASMN1; SMN2
	Trifluoroacetic Acid SCHEMBL3468551	0.77	MKNK1 (0.45)	ESR1BACE1
	SCHEMBL3468801	0.77	ENPP2 (0.49)	ESR1
	SCHEMBL3469301	0.77	ESR1 (0.42)	ESR1SMN1; SMN2HSD17B1ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.