SCHEMBL346814

SCHEMBL346814

C=C(C)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.69
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
FNTA P49354 2/20 0.42
FNTB P49356 2/20 0.42
GNPAT O15228 1/20 0.41
GRN P28799 1/20 0.41
SORT1 Q99523 1/20 0.41
MME P08473 4/20 0.40
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
THRB P10828 1/20 0.39
ALOX15 P16050 1/20 0.39
NFKB1 P19838 1/20 0.39
PTGS2 P35354 1/20 0.39
THPO P40225 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5891374 1.00 TGFBR1 (0.69) TGFBR1CA2CA4FNTAFNTB
Ammonia Solution, Strong SCHEMBL18141569 0.98 TGFBR1 (0.67) TGFBR1CA2CA4FNTAFNTB
Ammonia Solution, Strong SCHEMBL18140181 0.98 TGFBR1 (0.67) TGFBR1CA2CA4FNTAFNTB
SCHEMBL8176337 0.85 TGFBR1 (0.65) TGFBR1CA2GRNSORT1MAPT
SCHEMBL3440178 0.85 TGFBR1 (0.65) TGFBR1CA2GRNSORT1MAPT
SCHEMBL18141503 0.83 TGFBR1 (0.53) TGFBR1CA2CA4FNTAFNTB
Lithium Ion SCHEMBL18139956 0.83 TGFBR1 (0.53) TGFBR1CA2CA4FNTAFNTB
Potassium Ion SCHEMBL18140272 0.83 TGFBR1 (0.53) TGFBR1CA2CA4FNTAFNTB
SCHEMBL18141117 0.83 TGFBR1 (0.53) TGFBR1CA2CA4FNTAFNTB
SCHEMBL18139831 0.83 TGFBR1 (0.53) TGFBR1CA2CA4FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329845-B2 Divided redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2012-12-11 US claimed
US-7001963-B2 Cobalt imprinted polymer composition for selective removal of cobalt, process for preparation thereof, and process for removal of cobalt COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-02-21 US claimed
US-20050165136-A1 Glass-ionomer cements containing amino acids UAB RESEARCH FOUNDATION (US) 2005-07-28 US claimed
WO-2005063835-A1 COBALT IMPRINTED POLYMER COMPOSITION, PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-07-14 WO claimed
US-20050070677-A1 Cobalt imprinted polymer composition for selective removal of cobalt, process for preparation thereof, and process for removal of cobalt COUNCIL OF SCIENTIF AND INDUSTRIAL RESEARCH (IN) 2005-03-31 US claimed
US-20050070676-A1 Cobalt imprinted polymer composition for selective removal of cobalt, process for preparation thereof, and process for removal of cobalt COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-03-31 US claimed
EP-1503717-A1 GLASS-IONOMER CEMENTS CONTAINING AMINO ACIDS The UAB Research Foundation (US) 2005-02-09 EP claimed
WO-2003061606-A1 GLASS-IONOMER CEMENTS CONTAINING AMINO ACIDS UAB RESEARCH FOUNDATION (US) 2003-07-31 WO claimed
US-6583197-B1 Excellent sustained release of fluorine; free radical polymerizable unsaturated monomer having an acid group, acid-reactive fluoroaluminsilicate glass filler, water, solvent KABUSHIKI KAISHA SHOFU (JP) 2003-06-24 US claimed
US-5851546-A Polymer composition for controlled release of active ingredients in response to pH, and a process of preparing the same COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1998-12-22 US claimed
US-5780578-A Synthetic polymer exhibiting hydrolytic activity, its preparation and use for conversion of esters and amides to the corresponding alcohol and amine COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1998-07-14 US claimed
JP-9302042-A None JP disclosed
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
US-20240199494-A1 ZIRCONIA MOLDED BODY, ZIRCONIA PRE-SINTERED BODY, AND ZIRCONIA SINTERED BODY, AND METHODS OF PRODUCTION THEREOF Kuraray Noritake Dental lnc. (JP) 2024-06-20 US disclosed
EP-3848418-B1 DENTAL CURABLE COMPOSITION AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-05-22 EP disclosed
CN-1061978-A Surface active macromonomers BAUSCH & LOMB (US) 1992-06-17 CN disclosed
CN-1061786-A The surface coated of polymer articles BAUSCH & LOMB (US) 1992-06-10 CN disclosed
CN-1061785-A The surface modification of polymer articles BAUSCH & LOMB (US) 1992-06-10 CN disclosed
EP-0488258-A2 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 EP disclosed
US-4663409-A Alpha, beta-unsaturated carbonyl modified amino acid monomer and polymers for biomedical uses BAUSCH & LOMB INCORPORATED (US) 1987-05-05 US disclosed