Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.65 |
| ▸ | ECE1 | P42892 | 2/20 | 0.49 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.43 |
| ▸ | ITGAL | P20701 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440178 | 1.00 | TGFBR1 (0.65) | TGFBR1ECE1ITGB2ICAM1ITGAL | |
| SCHEMBL2954072 | 0.87 | TGFBR1 (0.52) | TGFBR1ECE1ITGB2ICAM1ITGAL | |
| SCHEMBL5891374 | 0.85 | TGFBR1 (0.69) | TGFBR1CA2ALDH1A1GRNSORT1 | |
| SCHEMBL346814 | 0.85 | TGFBR1 (0.69) | TGFBR1CA2ALDH1A1GRNSORT1 | |
| Ammonia Solution, Strong SCHEMBL18140181 | 0.83 | TGFBR1 (0.67) | TGFBR1CA2ALDH1A1GRNSORT1 | |
| Ammonia Solution, Strong SCHEMBL18141569 | 0.83 | TGFBR1 (0.67) | TGFBR1CA2ALDH1A1GRNSORT1 | |
| SCHEMBL28875839 | 0.82 | TGFBR1 (0.47) | TGFBR1ECE1ITGB2ICAM1ITGAL | |
| SCHEMBL8176290 | 0.82 | TGFBR1 (0.61) | TGFBR1CA2CA1KMT2AALOX15 | |
| SCHEMBL28875837 | 0.82 | TGFBR1 (0.47) | TGFBR1ECE1ITGB2ICAM1ITGAL | |
| SCHEMBL8176289 | 0.82 | TGFBR1 (0.61) | TGFBR1CA2CA1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135307-A | Carrier for cell delivery | 株式会社ITO | 2022-09-30 | — | — | CN | claimed |
| CN-114096514-A | Amino acid based polymerizable compounds and ophthalmic devices made therefrom | 强生视力健公司 | 2022-02-25 | — | — | CN | claimed |
| CN-114096514-B | Polymerizable amino acid-based compounds and ophthalmic devices made therefrom | 强生视力健公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-115135307-B | Cell delivery vehicle | 株式会社ITO | 2024-11-22 | — | — | CN | disclosed |
| CN-115135307-A | Carrier for cell delivery | 株式会社ITO | 2022-09-30 | — | — | CN | disclosed |
| CN-114096514-A | Amino acid based polymerizable compounds and ophthalmic devices made therefrom | 强生视力健公司 | 2022-02-25 | — | — | CN | disclosed |
| US-20210388142-A1 | AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM | JOHNSON & JOHNSON VISION CARE, INC. | 2021-12-16 | — | — | US | disclosed |
| US-6046289-A | FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS | FUJIFILM CORPORATION (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0488258-B1 | Propenamide derivatives, polymers, copolymers and use thereof | FUJI PHOTO FILM CO LTD (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0488258-A2 | Propenamide derivatives, polymers, copolymers and use thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210388142-A1 | AMINO ACID-BASED POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES PREPARED THEREFROM | ARGLU1, BCAT2, BCAT1 | TGFBR1 414/4885ECE1 1485/4885ITGB2 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.