Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20521155 | 0.84 | KLKB1 (0.43) | KLKB1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL29339783 | 0.81 | LTA4H (0.51) | LTA4HCYP19A1SIGMAR1CACNA1GCACNA1H | |
| SCHEMBL24483861 | 0.81 | LTA4H (0.51) | LTA4HCYP19A1SIGMAR1CACNA1GCACNA1H | |
| SCHEMBL21420053 | 0.78 | HSP90AA1 (0.43) | CYP19A1DGAT1KLKB1NPC1RAB9A | |
| SCHEMBL17459119 | 0.78 | HSP90AA1 (0.43) | DGAT1KLKB1NPC1RAB9AKMT2A | |
| SCHEMBL3696651 | 0.78 | GAA (0.46) | DGAT1KLKB1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2361709 | 0.77 | GAA (0.54) | DGAT1KLKB1KMT2AGAA | |
| SCHEMBL3467703 | 0.76 | NPBWR1 (0.49) | LTA4HSIGMAR1 | |
| SCHEMBL28170666 | 0.75 | GAA (0.43) | DGAT1KLKB1NPC1RAB9AKMT2A | |
| SCHEMBL3696648 | 0.75 | GAA (0.43) | CYP19A1DGAT1KLKB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077623-A1 | INTERMEDIATES AND PROCESSES FOR THE PREPARATION OF FLUOROGLYCOSIDE DERIVATIVES | SANOFI-AVENTIS (FR) | 2010-07-08 | — | — | WO | disclosed |