Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 8/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468419 | 1.00 | CYP2C19 (0.42) | CYP2C19CYP2D6LMNABLMALOX15 | |
| SCHEMBL3462868 | 1.00 | CYP2C19 (0.42) | CYP2C19CYP2D6LMNABLMALOX15 | |
| Hydrochloric Acid SCHEMBL17423104 | 0.98 | CYP2C19 (0.41) | CYP2C19CYP2D6LMNABLMALOX15 | |
| SCHEMBL3394263 | 0.83 | CYP2C19 (0.39) | CYP2C19CYP2D6LMNABLMALOX15 | |
| SCHEMBL23421119 | 0.75 | CYP2C19 (0.71) | CYP2C19CYP2D6LMNABLMALOX15 | |
| SCHEMBL13973941 | 0.75 | CYP2C19 (0.71) | CYP2C19CYP2D6LMNABLMALOX15 | |
| SCHEMBL16620358 | 0.75 | CYP2C19 (0.71) | CYP2C19CYP2D6LMNABLMALOX15 | |
| SCHEMBL2805632 | 0.75 | CYP2C19 (0.71) | CYP2C19CYP2D6LMNABLMALOX15 | |
| SCHEMBL4707192 | 0.75 | CYP2C19 (0.71) | CYP2C19CYP2D6LMNABLMALOX15 | |
| SCHEMBL12479952 | 0.75 | CYP2D6 (0.32) | CYP2C19CYP2D6LMNABLMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222026-A1 | Dibenzo[B,F][1,4]oxazepin-11-yl-N-Hydroxybenzamides as HDAC Inhibitors | FMR LLC | 2016-08-04 | — | — | US | disclosed |
| US-9193749-B2 | Dibenzo[b,f][1,4]oxazepin-11-yl-N-hydroxybenzamides as HDAC inhibitors | FORUM PHARMACEUTICALS, INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-9073922-B2 | Pyrrolo[2,3-B]pyridine CDK9 kinase inhibitors | ABBVIE, INC. (US) | 2015-07-07 | — | — | US | disclosed |
| US-20150051262-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2015-02-19 | — | — | US | disclosed |
| US-20140275027-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | ABBVIE INC. | 2014-09-18 | — | — | US | disclosed |
| EP-2771021-A2 | NMDA RECEPTOR MODULATORS AND USES THEREOF | North Western University (US) | 2014-09-03 | — | — | EP | disclosed |
| US-20140011988-A1 | Dibenzo[B,F][1,4]Oxazepin-11-yl-N-Hydroxybenzamides as HDAC Inhibitors | FMR LLC | 2014-01-09 | — | — | US | disclosed |
| WO-2013063120-A2 | NMDA RECEPTOR MODULATORS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2013-05-02 | — | — | WO | disclosed |
| WO-2010113035-A2 | PEPTIDE-BASED BETA TURN MIMETICS | UNIVERSITY OF MANITOBA (CA) | 2010-10-07 | — | — | WO | disclosed |
| US-20100256333-A1 | Peptide-Based Beta Turn Mimetics | UNIVERSITY OF MANITOBA (CA) | 2010-10-07 | — | — | US | disclosed |
| EP-1898940-A1 | INHIBITORS OF THE ALPHA2BETA 1/GPIA-IIA INTEGRIN | The Trustees of The University of Pennsylvania (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2006133338-A1 | INHIBITORS OF THE α2β1/GPIa-IIa INTEGRIN | THE TRUSTEES OF THE UNIVERSITY OF PENNESYLVANIA (US) | 2006-12-14 | — | — | WO | disclosed |
| EP-1123919-A1 | PROCESS FOR PRODUCING PEPTIDYL ALDEHYDES | Senju Pharmaceutical Co., Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051262-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN1, GRIN2A, GRIN3A | CYP2C19 3321/4885CYP2D6 1484/4885LMNA 4844/4885 |
| US-20100256333-A1 | Peptide-Based Beta Turn Mimetics | VIP, PTMA, PREP | CYP2C19 4610/4885CYP2D6 4645/4885LMNA 747/4885 |
| US-20140275027-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | CDK9, CDK19, CDK3 | CYP2C19 305/4885CYP2D6 942/4885LMNA 2275/4885 |
| US-20160222026-A1 | Dibenzo[B,F][1,4]oxazepin-11-yl-N-Hydroxybenzamides as HDAC Inhibitors | HDAC1, HDAC2, HDAC4 | CYP2C19 1980/4885CYP2D6 1008/4885LMNA 1258/4885 |
| US-20140011988-A1 | Dibenzo[B,F][1,4]Oxazepin-11-yl-N-Hydroxybenzamides as HDAC Inhibitors | HDAC1, HDAC2, HDAC4 | CYP2C19 1980/4885CYP2D6 1008/4885LMNA 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.