Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 2/20 | 0.54 |
| ▸ | IRS1 | P35568 | 2/20 | 0.54 |
| ▸ | GAB1 | Q13480 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468416 | 0.89 | P2RY1 (0.59) | ALDH1A1MEN1KMT2APOLBHSD17B10 | |
| SCHEMBL3467243 | 0.83 | P2RY1 (0.52) | ALDH1A1MEN1KMT2AHSD17B10AKT1 | |
| SCHEMBL3468247 | 0.80 | ALDH1A1 (0.66) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL1287357 | 0.75 | MAPT (0.61) | MEN1KMT2APOLBHPGDCA2 | |
| SCHEMBL3468791 | 0.75 | ALDH1A1 (0.55) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL5401641 | 0.74 | ALDH1A1 (0.82) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL5390639 | 0.73 | ALDH1A1 (0.73) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL3467605 | 0.72 | ALDH1A1 (0.57) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL5389556 | 0.71 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL5389533 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |