SCHEMBL5401641

SCHEMBL5401641

CCc1nnc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(F)cc3)cc2)s1

nearest known ligand 0.82

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.82
TDP1 Q9NUW8 3/20 0.82
ALOX12 P18054 3/20 0.82
KMT2A Q03164 13/20 0.81
MEN1 O00255 12/20 0.81
POLB P06746 2/20 0.81
KDM4E B2RXH2 2/20 0.71
L3MBTL1 Q9Y468 1/20 0.71
AKT1 P31749 1/20 0.71
HSD17B10 Q99714 2/20 0.69
PKM P14618 1/20 0.69
P2RY1 P47900 1/20 0.68
HPGD P15428 2/20 0.67
GBA1 P04062 1/20 0.67
RCE1 Q9Y256 1/20 0.67
LMNA P02545 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13212141 0.89 KMT2A (1.00) ALDH1A1TDP1ALOX12KMT2AMEN1
SCHEMBL31058614 0.89 KMT2A (0.81) ALDH1A1TDP1ALOX12KMT2AMEN1
SCHEMBL5401402 0.87 ALDH1A1 (1.00) ALDH1A1TDP1ALOX12KMT2AMEN1
SCHEMBL30209719 0.85 MEN1 (0.82) ALDH1A1TDP1ALOX12KMT2AMEN1
SCHEMBL14420720 0.85 MEN1 (0.80) ALDH1A1KMT2AMEN1POLBAKT1
SCHEMBL13212124 0.83 KMT2A (0.80) ALDH1A1TDP1ALOX12KMT2AMEN1
SCHEMBL287025 0.83 AKT1 (1.00) ALDH1A1KMT2AMEN1POLBAKT1
SCHEMBL13212128 0.83 MEN1 (1.00) ALDH1A1TDP1ALOX12KMT2AMEN1
SCHEMBL11893078 0.82 AKT1 (0.80) ALDH1A1KMT2AMEN1POLBAKT1
SCHEMBL14332232 0.81 GBA1 (1.00) ALDH1A1TDP1ALOX12KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692104-A1 CONJUGATE OF ANTIBODY AND FUNCTIONAL SUBSTANCE OR SALT OF SAID CONJUGATE, AND ANTIBODY INTERMEDIATE HAVING THIOL GROUP OR SALT OF SAID ANTIBODY INTERMEDIATE AJINOMOTO CO., INC. (JP) 2026-02-11 EP claimed
CN-119909064-A Cystamine derivative or salt thereof and application thereof in preparation of medicines with antioxidation effect 北京大学深圳研究生院 2025-05-02 CN claimed
CN-119338077-B Wind turbine running state prediction method and prediction system 四川省能投美姑新能源开发有限公司 2025-04-08 CN claimed
CN-119338077-A Wind turbine running state prediction method and prediction system 四川省能投美姑新能源开发有限公司 2025-01-21 CN claimed
CN-118909706-A Process for finely brewing beer by millet 鲁东大学 2024-11-08 CN claimed
CN-118879427-A Novel alcohol-free beer brewing process 鲁东大学 2024-11-01 CN claimed
CN-111511079-B Strobe-free dimming driver utilizing input valley bottom compensation 浙江凯耀照明有限责任公司 2024-10-29 CN claimed
WO-2024210178-A1 CONJUGATE OF ANTIBODY AND FUNCTIONAL SUBSTANCE OR SALT OF SAID CONJUGATE, AND ANTIBODY INTERMEDIATE HAVING THIOL GROUP OR SALT OF SAID ANTIBODY INTERMEDIATE 味の素株式会社 2024-10-10 WO claimed
US-20240251664-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-25 US claimed
CN-118234088-A Automatic temperature control circuit of LED lamp 宁波凯耀电器制造有限公司 2024-06-21 CN claimed
CN-217470334-U Time-delay turn-off circuit 宁波凯耀电器制造有限公司 2022-09-20 CN claimed
CN-217160060-U Color temperature switching de-pulsing circuit 宁波凯耀电器制造有限公司 2022-08-09 CN claimed
CN-216902800-U Excimer lamp exciter for solving EMI 浙江凯耀照明有限责任公司 2022-07-05 CN claimed
CN-114597115-A Excimer lamp exciter for solving EMI 浙江凯耀照明有限责任公司 2022-06-07 CN claimed
CN-114567174-A IC current electric measurement compensation circuit and application circuit thereof 浙江凯耀照明有限责任公司 2022-05-31 CN claimed
US-20070066614-A1 Ihibitors of 11-beta-hydroxy steroid dehydrogenase type 1 BIOVITRUM AB 2007-03-22 US claimed
US-7173030-B2 Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 BIOVITRUM AB (SE) 2007-02-06 US claimed
EP-1631558-A1 INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE I BIOVITRUM AB (SE) 2006-03-08 EP claimed
US-20050009821-A1 Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 BIOVITRUM AB 2005-01-13 US claimed
WO-2004103980-A1 INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE I BIOVITRUM AB (SE) 2004-12-02 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050009821-A1 Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 HSD11B1, HSD17B1, HSD11B2 ALDH1A1 53/4885TDP1 926/4885ALOX12 366/4885
US-20240251664-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME NES, NFE2L2, NUCB2 ALDH1A1 264/4885TDP1 2312/4885ALOX12 1405/4885
US-20070066614-A1 Ihibitors of 11-beta-hydroxy steroid dehydrogenase type 1 HSD11B1, HSD17B1, HSD17B11 ALDH1A1 36/4885TDP1 1572/4885ALOX12 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.