Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213688 | 1.00 | ALOX5 (0.47) | ALOX5CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL4590669 | 0.82 | CYP1A2 (0.68) | ALOX5CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL28958757 | 0.82 | CYP1A2 (0.68) | ALOX5CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL4589554 | 0.82 | CYP1A2 (0.68) | ALOX5CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL27860265 | 0.81 | CYP1A2 (0.43) | ALOX5CYP1A2SMN1; SMN2CYP2D6NPSR1 | |
| SCHEMBL25254767 | 0.81 | PKM (0.49) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL28989195 | 0.81 | CYP1A2 (0.47) | ALOX5CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL14966967 | 0.80 | ALOX5 (0.51) | ALOX5CYP1A2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL6223098 | 0.80 | ALOX5 (0.51) | ALOX5CYP1A2SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL20563823 | 0.80 | CYP1A2 (0.56) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820236-A | Histone acetyltransferase small molecule inhibitor and preparation method and application thereof | 复旦大学 | 2024-04-05 | — | — | CN | disclosed |
| WO-2010075270-A1 | 4, 6-DISUBSTITUTED 2-AMINO-PYRIMIDINES AS HISTAMINE H4 RECEPTOR MODULATORS | INCYTE CORPORATION (US) | 2010-07-01 | — | — | WO | disclosed |