Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.53 |
| ▸ | GSK3B | P49841 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468495 | 1.00 | GSK3A (0.53) | GSK3AGSK3BRAB9ANPC1GAA | |
| SCHEMBL3467058 | 0.86 | NPC1 (0.67) | GSK3AGSK3BRAB9ANPC1GAA | |
| SCHEMBL3467060 | 0.86 | NPC1 (0.67) | GSK3AGSK3BRAB9ANPC1GAA | |
| SCHEMBL3467761 | 0.86 | RAB9A (0.56) | GSK3AGSK3BRAB9ANPC1GAA | |
| SCHEMBL3467763 | 0.86 | RAB9A (0.56) | GSK3AGSK3BRAB9ANPC1GAA | |
| SCHEMBL14050056 | 0.83 | NPC1 (0.50) | GSK3AGSK3BRAB9ANPC1GAA | |
| SCHEMBL14028472 | 0.83 | RAB9A (0.50) | GSK3AGSK3BRAB9ANPC1GAA | |
| SCHEMBL8480872 | 0.81 | RAB9A (0.53) | GSK3AGSK3BRAB9ANPC1GAA | |
| SCHEMBL13273145 | 0.79 | SMN1; SMN2 (0.68) | GSK3BRAB9ANPC1GAASMN1; SMN2 | |
| SCHEMBL3467469 | 0.77 | RAB9A (0.51) | GSK3AGSK3BRAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074746-A1 | METHODS OF USE FOR OPSIN BINDING LIGANDS | BIKAM PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010074746-A1 | METHODS OF USE FOR OPSIN BINDING LIGANDS | BIKAM PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |