Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467060 | 1.00 | NPC1 (0.67) | NPC1RAB9AKMT2AGAAKDM4E | |
| SCHEMBL3468495 | 0.86 | GSK3A (0.53) | NPC1RAB9AKMT2AGAAKDM4E | |
| SCHEMBL3468490 | 0.86 | GSK3A (0.53) | NPC1RAB9AKMT2AGAAKDM4E | |
| SCHEMBL3467761 | 0.86 | RAB9A (0.56) | NPC1RAB9AKMT2AGAAKDM4E | |
| SCHEMBL3467763 | 0.86 | RAB9A (0.56) | NPC1RAB9AKMT2AGAAKDM4E | |
| SCHEMBL14028472 | 0.86 | RAB9A (0.50) | NPC1RAB9AKMT2AGAAKDM4E | |
| SCHEMBL3467604 | 0.85 | NPC1 (0.60) | NPC1RAB9AKMT2AGAAKDM4E | |
| SCHEMBL3467611 | 0.85 | NPC1 (0.60) | NPC1RAB9AKMT2AGAAKDM4E | |
| SCHEMBL14050056 | 0.83 | NPC1 (0.50) | NPC1RAB9AKMT2AGAAKDM4E | |
| SCHEMBL8481591 | 0.83 | NPC1 (0.55) | NPC1RAB9AKMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074746-A1 | METHODS OF USE FOR OPSIN BINDING LIGANDS | BIKAM PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010074746-A1 | METHODS OF USE FOR OPSIN BINDING LIGANDS | BIKAM PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |