SCHEMBL346859

SCHEMBL346859

COC(=O)C1(C)c2ccccc2-c2c1ccc1ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
NPSR1 Q6W5P4 2/20 0.43
ALDH1A1 P00352 5/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 3/20 0.38
HPGD P15428 3/20 0.38
POLB P06746 2/20 0.38
HSD17B10 Q99714 2/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
HTT P42858 1/20 0.38
WDR5 P61964 1/20 0.37
NCEH1 Q6PIU2 2/20 0.37
DNMT1 P26358 1/20 0.36
PDK2 Q15119 2/20 0.36
NSD2 O96028 1/20 0.35
OPRM1 P35372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4217613 0.80 ALDH1A1 (0.49) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL29892420 0.74 DNMT1 (0.42) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL13765088 0.74 DNMT1 (0.42) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL19771520 0.72 NSD2 (0.36) MAPTMEN1KMT2ANPSR1ALDH1A1
SCHEMBL21693384 0.71 DNMT1 (0.40) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL9610310 0.71 GSK3B (0.36) MAPTMEN1KMT2ANPSR1ALDH1A1
SCHEMBL18045128 0.70 DNMT1 (0.39) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL19974142 0.69 DNMT1 (0.43) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL29473425 0.69 DNMT1 (0.43) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL18826319 0.69 MAPT (0.36) MAPTMEN1KMT2ANPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-8048982-B2 Method for producing aromatic compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-01 US disclosed
EP-2241548-A1 Vanadium di-nuclear complex Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
EP-2241547-A1 Method for producing aromatic compound polymer Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
US-20090018309-A1 Method for Producing Aromatic Compound Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
EP-1767560-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER Sumitomo Chemical Company, Limited (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018309-A1 Method for Producing Aromatic Compound Polymer PAH, MAOA, AHR MAPT 2617/4885MEN1 4081/4885KMT2A 674/4885
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER PAH, MAOA, AHR MAPT 2638/4885MEN1 4122/4885KMT2A 715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.