SCHEMBL3468630

SCHEMBL3468630

Cc1cc(O)cc(CO)c1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.42
CHRM1 P11229 1/20 0.42
ALOX15 P16050 1/20 0.42
MAOA P21397 1/20 0.42
TBXA2R P21731 1/20 0.42
ADRA1A P35348 1/20 0.42
HTR2B P41595 1/20 0.42
SHBG P04278 1/20 0.42
ACHE P22303 2/20 0.39
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HSP90AA1 P07900 1/20 0.34
ATM Q13315 1/20 0.34
ESR2 Q92731 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPN11 Q06124 1/20 0.33
NUAK1 O60285 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17328717 0.87 ACHE (0.43) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL210420 0.83 CYP3A4 (0.44) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL15449429 0.81 SHBG (0.63) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL31553268 0.81 CYP3A4 (0.42) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL12964339 0.81 CYP3A4 (0.42) CYP3A4CHRM1ALOX15MAOATBXA2R
Methane SCHEMBL2220977 0.79 SHBG (0.61) CYP3A4CHRM1ALOX15MAOATBXA2R
Methane SCHEMBL27819850 0.79 SHBG (0.61) CYP3A4CHRM1ALOX15MAOATBXA2R
SCHEMBL30425753 0.78 SHBG (0.39) SHBGACHEALDH1A1SMN1; SMN2TDP1
SCHEMBL357123 0.78 SHBG (0.39) SHBGACHEALDH1A1SMN1; SMN2TDP1
SCHEMBL24373534 0.77 CYP3A4 (0.62) CYP3A4CHRM1ALOX15MAOATBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231515-B1 PROCESS FOR PRODUCING CARBON SUMITOMO CHEMICAL CO (JP) 2012-05-16 EP disclosed
US-20100316555-A1 PROCESS FOR PRODUCING CARBON Sumitomt Chemical Company, Limited (JP) 2010-12-16 US disclosed
EP-1414455-B1 ISOQUINOLINE INHIBITORS OF P38 VERTEX PHARMA (US) 2008-11-26 EP disclosed