Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRE | P23469 | 2/20 | 0.76 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.62 |
| ▸ | HPN | P05981 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244007 | 0.84 | PTPRE (0.65) | PTPREEPHX2ALOX5HPNHTT | |
| SCHEMBL3467221 | 0.82 | MAPT (0.77) | PTPREEPHX2ALOX5HPNHTT | |
| SCHEMBL3468124 | 0.79 | MAPT (0.57) | PTPREEPHX2ALOX5HPNHTT | |
| SCHEMBL3466713 | 0.78 | MEN1 (0.62) | EPHX2HPNHTTSMN1; SMN2MEN1 | |
| SCHEMBL3467090 | 0.78 | MEN1 (0.68) | EPHX2HPNHTTSMN1; SMN2MEN1 | |
| SCHEMBL3477465 | 0.76 | KMT2A (0.76) | HTTSMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL8569537 | 0.75 | HTT (1.00) | EPHX2HPNHTTSMN1; SMN2MEN1 | |
| SCHEMBL2029608 | 0.75 | HPN (1.00) | PTPREEPHX2ALOX5HPNHTT | |
| SCHEMBL8561964 | 0.75 | HTT (0.75) | EPHX2HPNHTTSMN1; SMN2MEN1 | |
| SCHEMBL5444273 | 0.74 | HPN (0.76) | PTPREEPHX2ALOX5HPNHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |