Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | HPN | P05981 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | PTPRE | P23469 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244007 | 0.89 | PTPRE (0.65) | MAPTHPNSMN1; SMN2HTTALOX5 | |
| SCHEMBL3468827 | 0.79 | PTPRE (0.76) | MAPTHPNSMN1; SMN2HTTALOX5 | |
| SCHEMBL3467221 | 0.77 | MAPT (0.77) | MAPTHPNSMN1; SMN2HTTALOX5 | |
| SCHEMBL8563911 | 0.76 | RAB9A (0.74) | MAPTHPNSMN1; SMN2HTTEPHX2 | |
| SCHEMBL5446202 | 0.76 | MAPT (0.59) | MAPTHPNSMN1; SMN2HTTPTPRE | |
| SCHEMBL5442348 | 0.76 | HPN (0.64) | MAPTHPNSMN1; SMN2HTTPTPRE | |
| SCHEMBL5447957 | 0.75 | MAPT (0.56) | MAPTHPNPTPRERAB9AMEN1 | |
| SCHEMBL3467467 | 0.75 | MEN1 (0.62) | MAPTHPNSMN1; SMN2HTTLMNA | |
| SCHEMBL2181677 | 0.75 | RAB9A (0.69) | MAPTHPNSMN1; SMN2HTTALOX5 | |
| SCHEMBL5435707 | 0.73 | HPN (0.62) | MAPTHPNSMN1; SMN2HTTPTPRE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |