Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | HTT | P42858 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | WRN | Q14191 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467090 | 0.86 | MEN1 (0.68) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL3467900 | 0.85 | ALDH1A1 (0.52) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL3467256 | 0.83 | MEN1 (0.74) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL3466712 | 0.80 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL8561964 | 0.79 | HTT (0.75) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL3468827 | 0.78 | PTPRE (0.76) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL3467467 | 0.78 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL3468497 | 0.76 | SMN1; SMN2 (0.70) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL3477465 | 0.76 | KMT2A (0.76) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL8559872 | 0.76 | HTT (0.73) | MEN1KMT2ASMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |