Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.31 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951328 | 0.90 | APP (0.49) | MAPTAPPSNCAALDH1A1GAA | |
| SCHEMBL17254449 | 0.88 | MAPT (0.49) | MAPTAPPSNCAALDH1A1GAA | |
| SCHEMBL17254448 | 0.83 | MAPT (0.44) | MAPTAPPSNCAALDH1A1GAA | |
| SCHEMBL19852804 | 0.83 | MAPT (0.48) | MAPTAPPSNCAALDH1A1MEN1 | |
| SCHEMBL4977529 | 0.77 | ENPP2 (0.40) | MAPTAPPSNCAALDH1A1GAA | |
| SCHEMBL13808727 | 0.74 | APP (0.86) | MAPTAPPSNCA | |
| SCHEMBL14527673 | 0.72 | MAPT (0.55) | MAPTAPPSNCAALDH1A1MEN1 | |
| SCHEMBL1727264 | 0.71 | APP (1.00) | MAPTAPPSNCA | |
| SCHEMBL12453200 | 0.71 | APP (1.00) | MAPTAPPSNCA | |
| SCHEMBL29528164 | 0.71 | APP (1.00) | MAPTAPPSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2186782-A1 | Methods for the purification of radiolabelled products using a solid-support scavanger | GE Healthcare Limited (GB) | 2010-05-19 | — | — | EP | claimed |