Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468916 | 0.90 | MAPT (0.55) | APPMAPTSNCAALDH1A1GAA | |
| SCHEMBL17254448 | 0.88 | MAPT (0.44) | APPMAPTSNCAALDH1A1GAA | |
| SCHEMBL17254449 | 0.86 | MAPT (0.49) | APPMAPTSNCAALDH1A1GAA | |
| SCHEMBL19852804 | 0.83 | MAPT (0.48) | APPMAPTSNCAALDH1A1HTT | |
| SCHEMBL17254446 | 0.79 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EGAAPOLB | |
| SCHEMBL4977529 | 0.77 | ENPP2 (0.40) | APPMAPTSNCAALDH1A1GAA | |
| SCHEMBL16366898 | 0.75 | PLAU (0.47) | ALDH1A1GAAPOLBMERTKKCNH3 | |
| SCHEMBL14527673 | 0.72 | MAPT (0.55) | APPMAPTSNCAALDH1A1KDM4E | |
| SCHEMBL15596831 | 0.70 | MAPT (0.54) | APPMAPTSNCAALDH1A1KDM4E | |
| SCHEMBL17472245 | 0.70 | MAPT (0.53) | APPMAPTSNCAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9186423-B1 | Compound of radiocontrast agent for tau protein | Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C. (TW) | 2015-11-17 | — | — | US | disclosed |
| US-20120238740-A1 | NON-POLAR AND POLAR LEAVING GROUPS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-09-20 | — | — | US | disclosed |
| EP-2454216-A1 | NON-POLAR AND POLAR LEAVING GROUPS | Bayer Pharma Aktiengesellschaft (DE) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011006610-A1 | NON-POLAR AND POLAR LEAVING GROUPS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238740-A1 | NON-POLAR AND POLAR LEAVING GROUPS | PGLS, RABGGTB, LNPEP | APP 1597/4885MAPT 3744/4885SNCA 2394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.