SCHEMBL3469028

SCHEMBL3469028

Cc1cc(C)c(C(=O)O)c(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.69
ACHE P22303 3/20 0.69
KMT2A Q03164 3/20 0.51
MAPK1 P28482 3/20 0.51
MEN1 O00255 2/20 0.51
ALDH1A1 P00352 2/20 0.51
HPGD P15428 1/20 0.51
ALOX15 P16050 1/20 0.51
HSD17B10 Q99714 1/20 0.51
POLB P06746 2/20 0.50
KDM4E B2RXH2 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MAPT P10636 2/20 0.48
IGFBP3 P17936 1/20 0.45
TPMT P51580 1/20 0.44
SELL P14151 1/20 0.44
SELP P16109 1/20 0.44
SELE P16581 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HCAR1 Q9BXC0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetaldehyde SCHEMBL10780089 0.92 CYP3A4 (0.60) CYP3A4ACHEKMT2AMAPK1MEN1
SCHEMBL632446 0.88 CYP3A4 (0.58) CYP3A4ACHEKMT2AMAPK1MEN1
SCHEMBL377596 0.85 KDM4E (0.55) CYP3A4ACHEKMT2AMAPK1MEN1
SCHEMBL21870 0.85 KDM4E (0.55) CYP3A4ACHEKMT2AMAPK1MEN1
SCHEMBL6912557 0.83 KDM4E (0.53) CYP3A4ACHEKMT2AMAPK1MEN1
SCHEMBL17558193 0.83 KDM4E (0.53) CYP3A4ACHEKMT2AMAPK1MEN1
SCHEMBL6912704 0.83 KDM4E (0.53) CYP3A4ACHEKMT2AMAPK1MEN1
SCHEMBL6915449 0.83 KDM4E (0.53) CYP3A4ACHEKMT2AMAPK1MEN1
Bicarbonate SCHEMBL7975060 0.83 KDM4E (0.53) CYP3A4ACHEKMT2AMAPK1MEN1
SCHEMBL6916749 0.83 KDM4E (0.53) CYP3A4ACHEKMT2AMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443742-B1 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 1997-10-01 EP claimed
US-5476754-A Presensitized; hydrophilic surface on substrate; light sensitive layer containing alkaline water-soluble photocrosslinkable copolycondensed diazo resin FUJI PHOTO FILM CO., LTD. (JP) 1995-12-19 US claimed
EP-0443742-A2 Presensitized plate for use in making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP claimed
EP-0415422-A2 Method for forming images FUJI PHOTO FILM CO., LTD. (JP) 1991-03-06 EP claimed
EP-0083971-B1 PHOTOSENSITIVE COMPOSITION KONICA CORPORATION (JP) 1987-04-01 EP claimed
US-4536465-A CONTAINING CARBOXY, OXY, AROMATIC COMPOUND AND ALDEHYDE OR KETONE WITH A NOVOLAK RESIN KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-08-20 US claimed
EP-0083971-A2 Photosensitive composition KONICA CORPORATION (JP) 1983-07-20 EP claimed
US-20240027903-A1 Resist Material And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20230215512-A1 Systems and Methods for Identifying and Expressing Gene Clusters THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2023-07-06 US disclosed
US-9956260-B1 Treatment of HIV-1 infection and AIDS THE J. DAVID GLADSTONE INSTITUTES (US) 2018-05-01 US disclosed
US-20170044160-A1 TETRACYCLINE COMPOUNDS TETRAPHASE PHARMACEUTICALS, INC. 2017-02-16 US disclosed
US-9315451-B2 Tetracycline compounds TETRAPHASE PHARMACEUTICALS, INC. (US) 2016-04-19 US disclosed
CN-103087521-B Polyimide resin composition containing polysiloxane and flexible substrate formed by same CHI MEI CORP 2015-05-13 CN disclosed
US-3992405-A ESPECIALLY FOR DYEING POLYACRYLIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1976-11-16 US disclosed
US-3991042-A Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus BAYER AKTIENGESELLSCHAFT (DT) 1976-11-09 US disclosed
US-3971807-A BENZINDOLE BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3959310-A BENZINDOLE BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3950347-A NAPHTHOLACTAM DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed
US-3948877-A POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240027903-A1 Resist Material And Patterning Process LBR, HNRNPU, EWSR1 CYP3A4 3750/4885ACHE 4873/4885KMT2A 882/4885
US-20170044160-A1 TETRACYCLINE COMPOUNDS TUBB, TUBA1C, TUBA1A CYP3A4 648/4885ACHE 3518/4885KMT2A 2833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.