Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3478615 | 0.81 | KMT2A (0.41) | KMT2APOLBMEN1GAAMAPK1 | |
| SCHEMBL5314641 | 0.78 | KMT2A (0.67) | KMT2APOLBMEN1GAAMAPK1 | |
| SCHEMBL13196418 | 0.76 | GAA (0.62) | KMT2APOLBMEN1GAAMAPK1 | |
| SCHEMBL3467484 | 0.72 | KMT2A (0.43) | KMT2APOLBMEN1GAAMAPK1 | |
| SCHEMBL3468905 | 0.70 | BRD4 (0.39) | KMT2A | |
| SCHEMBL14389908 | 0.68 | KMT2A (0.52) | KMT2APOLBMEN1GAAMAPK1 | |
| SCHEMBL3468222 | 0.64 | KMT2A (0.35) | KMT2APOLBMEN1GAAMAPK1 | |
| SCHEMBL2154996 | 0.64 | KMT2A (1.00) | KMT2APOLBMEN1GAAMAPK1 | |
| SCHEMBL5185805 | 0.63 | IDO1 (0.43) | KMT2APOLBMEN1GAAMAPT | |
| SCHEMBL3467415 | 0.62 | KMT2A (0.45) | KMT2APOLBMEN1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | disclosed |