Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2761926 | 0.82 | NQO2 (0.38) | BRD4KMT2ASMN1; SMN2NQO2 | |
| SCHEMBL3467484 | 0.66 | KMT2A (0.43) | BRD4KMT2A | |
| SCHEMBL3468222 | 0.65 | KMT2A (0.35) | KMT2A | |
| SCHEMBL13196473 | 0.64 | GAA (0.57) | BRD4KMT2ASMN1; SMN2PKLRNQO2 | |
| SCHEMBL15520597 | 0.60 | NR3C1 (0.52) | NPC1RAB9ANR3C1 | |
| SCHEMBL16803210 | 0.59 | BRD4 (0.70) | BRD4SMN1; SMN2 | |
| SCHEMBL749632 | 0.59 | HTR1A (0.39) | — | |
| SCHEMBL30213370 | 0.59 | CNR1 (0.37) | BRD4SMN1; SMN2 | |
| SCHEMBL9097140 | 0.59 | KMT2A (0.67) | KMT2ASMN1; SMN2 | |
| SCHEMBL11516736 | 0.58 | ALDH1A1 (0.39) | BRD4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | claimed |