Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467484 | 0.68 | KMT2A (0.43) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL2762571 | 0.63 | KMT2A (0.41) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL13196473 | 0.63 | GAA (0.57) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL9098061 | 0.62 | KMT2A (0.61) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL2825338 | 0.61 | MAPK1 (0.54) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL13196445 | 0.60 | CNR2 (0.57) | POLBALDH1A1CNR2 | |
| SCHEMBL3468468 | 0.60 | KMT2A (0.48) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL2154996 | 0.60 | KMT2A (1.00) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL2781617 | 0.59 | KMT2A (0.57) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL28119211 | 0.59 | IDO1 (0.47) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | disclosed |