Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 1.00 |
| ▸ | MAOA | P21397 | 4/20 | 1.00 |
| ▸ | F3 | P13726 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | XDH | P47989 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | P4HB | P07237 | 1/20 | 0.75 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.72 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.72 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.72 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.72 |
| ▸ | BCHE | P06276 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323431 | 1.00 | MAOB (1.00) | MAOBMAOAF3MAPTXDH | |
| SCHEMBL5058785 | 1.00 | MAOB (1.00) | MAOBMAOAF3MAPTXDH | |
| SCHEMBL9818339 | 1.00 | MAOB (1.00) | MAOBMAOAF3MAPTXDH | |
| 4,4'-Dimethoxychalcone SCHEMBL978242 | 0.92 | F3 (1.00) | MAOBMAOAF3MAPTXDH | |
| 4,4'-Dimethoxychalcone SCHEMBL978243 | 0.92 | F3 (1.00) | MAOBMAOAF3MAPTXDH | |
| SCHEMBL1659833 | 0.87 | ESR1 (0.86) | MAOBMAOAF3MAPTMEN1 | |
| SCHEMBL1659832 | 0.87 | ESR1 (0.86) | MAOBMAOAF3MAPTMEN1 | |
| SCHEMBL1321123 | 0.86 | HDAC3 (0.82) | MAOBMAOAF3MAPTXDH | |
| SCHEMBL29040010 | 0.86 | F3 (0.82) | MAOBMAOAF3MAPTXDH | |
| SCHEMBL1321125 | 0.86 | HDAC3 (0.82) | MAOBMAOAF3MAPTXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6941051-B2 | Method for producing non-linear optical organic crystal film | REVEO, INC. (US) | 2005-09-06 | — | — | US | claimed |
| US-20040033038-A1 | Method for producing non-linear optical organic crystal film | XU JIANJUN (US) | 2004-02-19 | — | — | US | claimed |
| US-6577798-B2 | Method for producing non-linear optical organic crystal film | REVEO, INC. | 2003-06-10 | — | — | US | claimed |
| US-20020041427-A1 | Method for producing non-linear optical organic crystal film | REVEO, INC. | 2002-04-11 | — | — | US | claimed |
| WO-2002008828-A2 | COMPOSITE NONLINEAR OPTICAL FILM, METHOD OF PRODUCING THE SAME AND APPLICATIONS OF THE SAME | REVEO, INC. (US) | 2002-01-31 | — | — | WO | claimed |
| WO-2002006890-A2 | METHOD FOR PRODUCING NON-LINEAR OPTICAL ORGANIC CRYSTAL FILM | REVEO, INC. (US) | 2002-01-24 | — | — | WO | claimed |
| US-6303056-B1 | Composite nonlinear optical film, method of producing the same and applications of the same | REVEO, INC. | 2001-10-16 | — | — | US | claimed |
| US-8716532-B2 | One pot multicomponent synthesis of some novel hydroxy stilbene derivatives with alpha, beta-carbonyl conjugation under microwave irradiation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-05-06 | — | — | US | disclosed |
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-28 | — | — | US | disclosed |
| WO-2010113005-A2 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-10-07 | — | — | WO | disclosed |
| US-20080146574-A1 | Heterocycle Substituted Carboxylic Acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC | 2008-06-19 | — | — | US | disclosed |
| US-7329680-B2 | Heterocycle substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2008-02-12 | — | — | US | disclosed |
| EP-1844043-A2 | HETEROCYCLE SUBSTITUTED CARBOXYLIC ACIDS FOR THE TREATMENT OF DIABETES | The Institutes for Pharmaceutical Discovery, LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| US-6229047-B1 | NONLINEAR OPTICAL MATERIAL WHICH IS CHARACTERIZED AS HAVING A HIGH MACROSCOPIC DIPOLE MOMENT ACHIEVED THROUGH PARALLEL PACKING OF DIPOLAR MOLECULES (CRYSTALLINE AZINE BRIDGED DI-ARENE) | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2001-05-08 | — | — | US | disclosed |
| EP-0368169-B1 | Method for producing organic crystal | SUMITOMO ELECTRIC INDUSTRIES (JP) | 1995-07-19 | — | — | EP | disclosed |
| US-5363797-A | Method for producing organic crystal and crystal growth cell therefor | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0262672-B1 | NON-LINEAR OPTICAL ARTICLE | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0368169-A1 | Method for producing organic crystal | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1990-05-16 | — | — | EP | disclosed |
| US-4892681-A | BENZALACETOPHENONE DERIVATIVE, RADIATION TRANSPARENT | NIPPON OIL AND FATS CO., LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0262672-A1 | Non-linear optical article | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1988-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | SIK1, SIK2, HCK | MAOB 1286/4885MAOA 2456/4885F3 1903/4885 |
| US-20080146574-A1 | Heterocycle Substituted Carboxylic Acids | PTPRC, PTPRS, PTPRJ | MAOB 378/4885MAOA 842/4885F3 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.