Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821358 | 0.83 | RAB9A (0.47) | CSNK1DSMN1; SMN2ALDH1A1RAB9AGAA | |
| SCHEMBL2824781 | 0.82 | PPARG (0.50) | PPARGPPARDPPARASMN1; SMN2TDP1 | |
| SCHEMBL3478631 | 0.81 | RAB9A (0.43) | CSNK1DSMN1; SMN2ALDH1A1RAB9AGAA | |
| SCHEMBL3469511 | 0.80 | PPARA (0.48) | PPARGPPARDPPARASMN1; SMN2TDP1 | |
| SCHEMBL2818927 | 0.68 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1RAB9AGAANPC1 | |
| SCHEMBL2530325 | 0.67 | CSNK1D (0.43) | CSNK1DSMN1; SMN2ALDH1A1RAB9AMAPT | |
| SCHEMBL2820962 | 0.66 | PPARG (0.54) | PPARGPPARDPPARASMN1; SMN2ALDH1A1 | |
| SCHEMBL20202573 | 0.64 | MAPK1 (0.51) | SMN1; SMN2TDP1ALDH1A1RAB9ANPSR1 | |
| SCHEMBL10598737 | 0.64 | RAB9A (0.56) | SMN1; SMN2ALDH1A1RAB9AMAPK1MAPT | |
| SCHEMBL3469303 | 0.63 | MEN1 (0.33) | ALDH1A1RAB9AGAAMAPTADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071813-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-α | ARYX THERAPEUTICS, INC. (US) | 2010-06-24 | — | — | WO | disclosed |