Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.75 |
| ▸ | HSD11B2 | P80365 | 10/20 | 0.75 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.75 |
| ▸ | CES2 | O00748 | 4/20 | 0.75 |
| ▸ | CES1 | P23141 | 4/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.75 |
| ▸ | PRKCH | P24723 | 1/20 | 0.75 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.75 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.75 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | APEX1 | P27695 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469345 | 1.00 | HSD11B1 (0.75) | HSD11B1HSD11B2PTPN1CES2CES1 | |
| SCHEMBL23747120 | 0.91 | CES2 (0.75) | HSD11B1HSD11B2PTPN1CES2CES1 | |
| SCHEMBL22324319 | 0.91 | HSD11B1 (0.73) | HSD11B1HSD11B2PTPN1CES2CES1 | |
| SCHEMBL21352622 | 0.91 | CES2 (0.75) | HSD11B1HSD11B2PTPN1CES2CES1 | |
| SCHEMBL1721845 | 0.91 | CES2 (0.75) | HSD11B1HSD11B2PTPN1CES2CES1 | |
| SCHEMBL1721221 | 0.90 | HSD11B1 (0.76) | HSD11B1HSD11B2PTPN1CES2CES1 | |
| SCHEMBL1722126 | 0.90 | HSD11B1 (0.65) | HSD11B1HSD11B2PTPN1CES2CES1 | |
| SCHEMBL1721856 | 0.88 | HSD11B1 (0.63) | HSD11B1HSD11B2PTPN1CES2CES1 | |
| SCHEMBL13056383 | 0.88 | HSD11B1 (0.56) | HSD11B1HSD11B2PTPN1CES2CES1 | |
| SCHEMBL11789935 | 0.88 | HSD11B2 (0.59) | HSD11B1HSD11B2PTPN1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139692-A2 | ANTIVIRAL TRITERPENE DERIVATIVES | SAVIRA PHARMACEUTICALS GMBH (AT) | 2010-12-09 | — | — | WO | claimed |
| WO-2010139692-A2 | ANTIVIRAL TRITERPENE DERIVATIVES | SAVIRA PHARMACEUTICALS GMBH (AT) | 2010-12-09 | — | — | WO | disclosed |