Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL729742 | 0.87 | MEN1 (0.37) | HDAC1PPARGMEN1KMT2AHRH3 | |
| SCHEMBL727316 | 0.87 | MEN1 (0.37) | HDAC1PPARGMEN1KMT2AHRH3 | |
| SCHEMBL729234 | 0.86 | MEN1 (0.38) | HDAC1PPARGMEN1KMT2AHRH3 | |
| SCHEMBL1685013 | 0.85 | MEN1 (0.36) | HDAC1PPARGMEN1KMT2ARARB | |
| SCHEMBL3175452 | 0.85 | MEN1 (0.36) | HDAC1PPARGMEN1KMT2ARARB | |
| SCHEMBL727594 | 0.84 | MEN1 (0.38) | HDAC1MEN1KMT2AHRH3SMPD1 | |
| SCHEMBL11936601 | 0.83 | MEN1 (0.38) | MEN1KMT2AHRH3RARBGAA | |
| SCHEMBL727965 | 0.83 | PRMT1 (0.53) | HRH3 | |
| SCHEMBL3262577 | 0.82 | MEN1 (0.39) | MEN1KMT2AHRH3RARBGAA | |
| SCHEMBL3247028 | 0.82 | MEN1 (0.34) | HDAC1PPARGMEN1KMT2ARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177219-A1 | PREVENTIVE AGENT OR THERAPEUTIC AGENT FOR DISEASE CAUSED BY ABNORMAL BONE METABOLISM | Teijin Pharma Limited (JP) | 2010-04-21 | — | — | EP | disclosed |