Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 12/20 | 0.49 |
| ▸ | FYN | P06241 | 5/20 | 0.46 |
| ▸ | RAD52 | P43351 | 2/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469340 | 0.80 | FYN (0.62) | TTKFYNRAD52 | |
| SCHEMBL2401175 | 0.80 | MAPKAPK5 (0.60) | TTK | |
| SCHEMBL3467955 | 0.78 | TTK (0.50) | TTKFYNRAD52 | |
| SCHEMBL3469410 | 0.75 | RAD52 (0.62) | FYNRAD52BRAF | |
| SCHEMBL8241606 | 0.74 | AURKA (0.58) | — | |
| SCHEMBL15858028 | 0.74 | BRAF (0.50) | BRAF | |
| SCHEMBL3469745 | 0.74 | ABL1 (0.51) | TTK | |
| SCHEMBL1674115 | 0.74 | MAPKAPK5 (0.57) | TTK | |
| SCHEMBL22122904 | 0.74 | FYN (0.52) | TTKFYNRAD52 | |
| SCHEMBL30172068 | 0.74 | FYN (0.52) | TTKFYNRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |