SCHEMBL3469361

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3468894	1.00	ESR1 (0.41)	ESR1ESR2SLC6A3PGRCHRM2
	SCHEMBL3896286	0.80	ESR1 (0.54)	ESR1ESR2SLC6A3PGRCHRM2
	SCHEMBL3468370	0.80	ESR1 (0.54)	ESR1ESR2SLC6A3PGRCHRM2
	SCHEMBL27653097	0.78	ESR1 (0.55)	ESR1ESR2PTGER2ERN1TOP2A
	SCHEMBL3902681	0.78	ESR1 (0.51)	ESR1ESR2SLC6A3PGRCHRM2
	SCHEMBL3469301	0.77	ESR1 (0.42)	ESR1SLC6A3SLC6A4PTGER2ERN1
	SCHEMBL3468357	0.75	TAAR1 (0.41)	ESR1ESR2SLC6A3PGRCHRM2
	SCHEMBL3468861	0.75	TAAR1 (0.41)	ESR1ESR2SLC6A3PGRCHRM2
	SCHEMBL3469146	0.74	MMP3 (0.59)	ESR1ESR2SLC6A3PGRCHRM2
	SCHEMBL19700438	0.72	ESR1 (0.50)	ESR1ESR2SLC6A3PGRCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.