SCHEMBL3896286

SCHEMBL3896286

Oc1ccc(C(=C2CCCCC2)c2ccc(O)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.54
ESR2 Q92731 7/20 0.54
PGR P06401 1/20 0.52
CHRM2 P08172 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
AR P10275 1/20 0.52
CHRM1 P11229 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A3 Q01959 1/20 0.52
PSMB1 P20618 2/20 0.45
PSMB5 P28074 2/20 0.45
PSMB2 P49721 2/20 0.45
HPGD P15428 5/20 0.42
MAPT P10636 5/20 0.42
ALDH1A1 P00352 3/20 0.42
KMT2A Q03164 3/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3468370 1.00 ESR1 (0.54) ESR1ESR2PGRCHRM2ADORA3
SCHEMBL3902681 0.98 ESR1 (0.51) ESR1ESR2PGRCHRM2ADORA3
SCHEMBL19700438 0.90 ESR1 (0.50) ESR1ESR2PGRCHRM2ADORA3
SCHEMBL3467561 0.90 ALOX15 (0.50) ESR1ESR2PGRCHRM2ADORA3
SCHEMBL3468339 0.90 ALOX15 (0.50) ESR1ESR2PGRCHRM2ADORA3
SCHEMBL17845143 0.90 ESR1 (0.48) ESR1ESR2PGRCHRM2ADORA3
SCHEMBL3468461 0.90 ALOX15 (0.50) ESR1ESR2PGRCHRM2ADORA3
SCHEMBL3468640 0.88 CA2 (0.59) ESR1ESR2PGRCHRM2ADORA3
SCHEMBL3468092 0.88 CA2 (0.59) ESR1ESR2PGRCHRM2ADORA3
SCHEMBL3468873 0.88 CA2 (0.59) ESR1ESR2PGRCHRM2ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
EP-3266771-B1 SYNTHESIS OF PHOTOACTIVABLE CAGED CYCLOFEN-OH AND DERIVATIVES THEREOF PARIS SCIENCES LETTRES QUARTIER LATIN (FR) 2019-02-20 EP disclosed
WO-2017212059-A1 SYNTHESIS OF PHOTOACTIVABLE CAGED CYCLOFEN-OH AND DERIVATIVES THEREOF PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) 2017-12-14 WO disclosed
WO-2009072002-A2 BISPHENOLS IN CANCER THERAPY UNIVERSITY OF MANITOBA (US) 2009-06-11 WO disclosed
WO-2009072002-A2 BISPHENOLS IN CANCER THERAPY UNIVERSITY OF MANITOBA (US) 2009-06-11 WO disclosed