Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.60 |
| ▸ | MMP2 | P08253 | 5/20 | 0.60 |
| ▸ | MMP9 | P14780 | 5/20 | 0.60 |
| ▸ | TTR | P02766 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | APP | P05067 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535158 | 0.92 | TTR (0.66) | MMP1MMP2MMP9TTRKDM4E | |
| SCHEMBL2981331 | 0.83 | MAPT (0.59) | MMP1MMP2MMP9MAPTAKR1B10 | |
| Caffeic Acid SCHEMBL15971329 | 0.78 | KDM4E (0.89) | MMP1MMP2MMP9TTRKDM4E | |
| Caffeic Acid SCHEMBL28110812 | 0.78 | KDM4E (0.96) | MMP1MMP2MMP9TTRKDM4E | |
| Caffeic Acid SCHEMBL28110813 | 0.78 | KDM4E (0.96) | MMP1MMP2MMP9TTRKDM4E | |
| SCHEMBL28461467 | 0.78 | CYP1B1 (0.58) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL28463285 | 0.78 | CYP1B1 (0.58) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL28086925 | 0.76 | TTR (0.65) | MMP1MMP2MMP9TTRKDM4E | |
| Caffeic Acid SCHEMBL7064846 | 0.76 | KDM4E (1.00) | MMP1MMP2MMP9TTRKDM4E | |
| Caffeic Acid SCHEMBL1262229 | 0.76 | KDM4E (1.00) | MMP1MMP2MMP9TTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716532-B2 | One pot multicomponent synthesis of some novel hydroxy stilbene derivatives with alpha, beta-carbonyl conjugation under microwave irradiation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-05-06 | — | — | US | disclosed |
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-28 | — | — | US | disclosed |
| WO-2010113005-A2 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | SIK1, SIK2, HCK | MMP1 4451/4885MMP2 4311/4885MMP9 4260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.