SCHEMBL6535158

SCHEMBL6535158

O=C(O)C(C=Cc1ccc(O)c(O)c1)=Cc1ccc(O)c(O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 4/20 0.66
HSD17B10 Q99714 3/20 0.66
KDM4E B2RXH2 2/20 0.66
MAPT P10636 2/20 0.66
APP P05067 2/20 0.66
DPP4 P27487 2/20 0.66
MMP1 P03956 2/20 0.66
MMP2 P08253 2/20 0.66
MMP9 P14780 2/20 0.66
TDP1 Q9NUW8 2/20 0.66
AKR1B10 O60218 2/20 0.66
AKR1B1 P15121 2/20 0.66
MEN1 O00255 1/20 0.66
HDAC3 O15379 1/20 0.66
CA12 O43570 1/20 0.66
ALDH1A1 P00352 1/20 0.66
CA1 P00915 1/20 0.66
CA2 P00918 1/20 0.66
LMNA P02545 1/20 0.66
GLA P06280 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3469448 0.92 MMP1 (0.60) TTRHSD17B10KDM4EMAPTAPP
SCHEMBL7585198 0.80 HSD17B10 (0.62) TTRHSD17B10KDM4EMAPTAPP
Caffeic Acid SCHEMBL29353048 0.80 KDM4E (1.00) TTRHSD17B10KDM4EMAPTAPP
Caffeic Acid SCHEMBL7064846 0.80 KDM4E (1.00) TTRHSD17B10KDM4EMAPTAPP
Caffeic Acid SCHEMBL29447135 0.80 KDM4E (1.00) TTRHSD17B10KDM4EMAPTAPP
Caffeic Acid SCHEMBL23358 0.80 KDM4E (1.00) TTRHSD17B10KDM4EMAPTAPP
Caffeic Acid SCHEMBL1262229 0.80 KDM4E (1.00) TTRHSD17B10KDM4EMAPTAPP
Caffeic Acid SCHEMBL3682144 0.80 KDM4E (1.00) TTRHSD17B10KDM4EMAPTAPP
Caffeic Acid SCHEMBL21114743 0.80 KDM4E (1.00) TTRHSD17B10KDM4EMAPTAPP
Caffeic Acid SCHEMBL30501140 0.80 KDM4E (1.00) TTRHSD17B10KDM4EMAPTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1206255-A4 COMPOUNDS OBTAINED FROM i SALVIA SPECIES /i HAVING ANTIVIRAL ACTIVITY UNIV GEORGETOWN (US) 2004-02-11 EP claimed
WO-2001000199-A9 COMPOUNDS OBTAINED FROM SALVIA SPECIES HAVING ANTIVIRAL ACTIVITY UNIV GEORGETOWN (US) 2002-06-13 WO claimed
EP-1206255-A1 COMPOUNDS OBTAINED FROM i SALVIA SPECIES /i HAVING ANTIVIRAL ACTIVITY GEORGETOWN UNIVERSITY (US) 2002-05-22 EP claimed
EP-1089747-A1 COMPOUNDS OBTAINED FROM SALVIA SPECIES HAVING ANTIVIRAL ACTIVITY GEORGETOWN UNIVERSITY (US) 2001-04-11 EP claimed
WO-2001000199-A1 COMPOUNDS OBTAINED FROM SALVIA SPECIES HAVING ANTIVIRAL ACTIVITY GEORGETOWN UNIVERSITY (US) 2001-01-04 WO claimed
WO-1999066942-A9 COMPOUNDS OBTAINED FROM SALVIA SPECIES HAVING ANTIVIRAL ACTIVITY UNIV GEORGETOWN (US) 2000-06-22 WO claimed
WO-1999066942-A1 COMPOUNDS OBTAINED FROM SALVIA SPECIES HAVING ANTIVIRAL ACTIVITY GEORGETOWN UNIVERSITY (US) 1999-12-29 WO claimed