Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855414 | 0.73 | — | — | |
| SCHEMBL15409919 | 0.69 | EGLN2 (0.34) | EGLN2 | |
| SCHEMBL16542598 | 0.68 | AR (0.32) | — | |
| SCHEMBL31463746 | 0.66 | EGLN2 (0.34) | EGLN2 | |
| SCHEMBL31350312 | 0.65 | — | — | |
| SCHEMBL24198342 | 0.63 | EGLN2 (0.36) | EGLN2 | |
| SCHEMBL25473240 | 0.63 | GRM5 (0.33) | — | |
| SCHEMBL18078323 | 0.63 | KDM4E (0.37) | — | |
| SCHEMBL18048260 | 0.63 | AR (0.33) | — | |
| SCHEMBL16060117 | 0.63 | LMNA (0.34) | CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071885-A1 | PYRROLOTRIAZINES AS ALK AND JAK2 INHIBITORS | CEPHALON, INC. (US) | 2010-06-24 | — | — | WO | disclosed |