Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 13/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | INSR | P06213 | 2/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10267138 | 0.78 | EGLN2 (0.32) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL26017699 | 0.77 | TGFBR1 (0.31) | — | |
| SCHEMBL16542598 | 0.76 | AR (0.32) | IRAK4 | |
| SCHEMBL18078323 | 0.74 | KDM4E (0.37) | KDM4E | |
| SCHEMBL26024444 | 0.74 | — | — | |
| SCHEMBL24198342 | 0.74 | EGLN2 (0.36) | GRM5 | |
| SCHEMBL34471810 | 0.65 | ALDH1A1 (0.38) | TNFKDM4EALDH1A1 | |
| SCHEMBL18048260 | 0.65 | AR (0.33) | — | |
| SCHEMBL3469449 | 0.63 | EGLN2 (0.31) | — | |
| SCHEMBL7455400 | 0.63 | KDM4E (0.64) | GRM5ADORA2AADORA1MAP4K4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180434-A1 | PB2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |