Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.42 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.42 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.42 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | RAD52 | P43351 | 3/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319304 | 0.98 | — | — | |
| Iodide SCHEMBL1816327 | 0.96 | SMN1; SMN2 (0.41) | KMT2AHSP90AA1SMN1; SMN2HTTRAD52 | |
| Iodide SCHEMBL1226159 | 0.96 | SMN1; SMN2 (0.41) | KMT2AHSP90AA1SMN1; SMN2HTTRAD52 | |
| Hydrochloric Acid SCHEMBL365125 | 0.96 | KMT2A (0.42) | KMT2AHSP90AA1SMN1; SMN2HTTRAD52 | |
| SCHEMBL16992935 | 0.96 | CHRM2 (0.39) | KMT2AHSP90AA1SMN1; SMN2HTTRAD52 | |
| Hydrochloric Acid SCHEMBL19031751 | 0.94 | KMT2A (0.41) | KMT2AHSP90AA1SMN1; SMN2HTTRAD52 | |
| Bromide SCHEMBL14896254 | 0.94 | KMT2A (0.50) | KMT2AHSP90AA1SMN1; SMN2HTTRAD52 | |
| Bromide SCHEMBL5348732 | 0.92 | KMT2A (0.53) | KMT2AHSP90AA1SMN1; SMN2HTTRAD52 | |
| Bromide SCHEMBL22027172 | 0.92 | KMT2A (0.53) | KMT2AHSP90AA1SMN1; SMN2HTTRAD52 | |
| Bromide SCHEMBL22027189 | 0.92 | KMT2A (0.53) | KMT2AHSP90AA1SMN1; SMN2HTTRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4341315-A1 | IMIDAZOLIUM-BASED POLY(IONIC LIQUID)S AND USE THEREFORE | Versum Materials US, LLC (US) | 2024-03-27 | — | — | EP | claimed |
| CN-113346058-A | Method for preparing bimetallic sulfide and carbon compound under ionic gel system | 大连理工大学 | 2021-09-03 | — | — | CN | claimed |
| EP-1663921-A2 | METHOD FOR PRODUCING HALOALKANES FROM ALCOHOLS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-07 | — | — | EP | claimed |
| WO-2005026089-A2 | METHOD FOR PRODUCING HALOALKANES FROM ALCOHOLS | BASF AKTIENGESELLSCHAFT (DE) | 2005-03-24 | — | — | WO | claimed |
| US-12325798-B1 | Compositions containing lignocellulosic biomass residues, polymer composites made therefrom, and methods of making lignocellulosic biomass residues and polymer composites containing them | PLANTOON TECHNOLOGIES KFT. (HU) | 2025-06-10 | — | — | US | disclosed |
| US-12325799-B1 | Compositions containing lignocellulosic biomass residues, polymer composites made therefrom, and methods of making lignocellulosic biomass residues and polymer composites containing them | PLANTOON TECHNOLOGIES KFT. (HU) | 2025-06-10 | — | — | US | disclosed |
| US-12018156-B1 | Compositions containing lignocellulosic biomass residues, polymer composites made therefrom, and methods of making lignocellulosic biomass residues and polymer composites containing them | PLANTOON TECHNOLOGIES KFT. (HU) | 2024-06-25 | — | — | US | disclosed |
| US-12012514-B1 | Compositions containing lignocellulosic biomass residues, polymer composites made therefrom, and methods of making lignocellulosic biomass residues and polymer composites containing them | PLANTOON TECHNOLOGIES KFT. (HU) | 2024-06-18 | — | — | US | disclosed |
| CN-112251240-B | Quaternary ammonium salt ionic liquid crystal polymer with temperature control electronic switch performance and preparation method and application thereof | 东北大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-112251240-A | Quaternary ammonium salt ionic liquid crystal polymer with temperature control electronic switch performance and preparation method and application thereof | 东北大学 | 2021-01-22 | — | — | CN | disclosed |
| US-8716532-B2 | One pot multicomponent synthesis of some novel hydroxy stilbene derivatives with alpha, beta-carbonyl conjugation under microwave irradiation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-05-06 | — | — | US | disclosed |
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-28 | — | — | US | disclosed |
| US-20120157579-A1 | Azolium Ionomer Derivatives of Halogenated Polymers | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-06-21 | — | — | US | disclosed |
| WO-2012075574-A1 | AZOLIUM IONOMER DERIVATIVES OF HALOGENATED POLYMERS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-06-14 | — | — | WO | disclosed |
| WO-2010113005-A2 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165567-A1 | ONE POT MULTICOMPONENT SYNTHESIS OF SOME NOVEL HYDROXY STILBENE DERIVATIVES WITH ALPHA, BETA-CARBONYL CONJUGATION UNDER MICROWAVE IRRADIATION | SIK1, SIK2, HCK | CHRM2 4520/4885CHRM1 3968/4885ACHE 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.