Hydrochloric Acid

Hydrochloric Acid

SCHEMBL365125

CCCC[n+]1cc[nH]c1.[Cl-]

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 2/20 0.39
CHRM1 known ✓ P11229 2/20 0.39
ACHE known ✓ P22303 2/20 0.39
SLC6A2 known ✓ P23975 2/20 0.39
SLC6A3 known ✓ Q01959 2/20 0.39
CHRM3 known ✓ P20309 1/20 0.38
KMT2A Q03164 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
MAPK1 P28482 1/20 0.42
CASP2 P42575 1/20 0.42
RAD52 P43351 3/20 0.41
HSPD1 P10809 1/20 0.41
HSPE1 P61604 1/20 0.41
ADRA2A P08913 2/20 0.39
ADORA3 P0DMS8 2/20 0.39
SLC6A4 P31645 2/20 0.39
ABCB11 O95342 1/20 0.39
ESR1 P03372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL19031751 0.98 KMT2A (0.41) KMT2ASMN1; SMN2MEN1MAPTMAPK1
SCHEMBL319304 0.98
SCHEMBL16992935 0.96 CHRM2 (0.39) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Bromide SCHEMBL3469640 0.96 KMT2A (0.42) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Iodide SCHEMBL1816327 0.96 SMN1; SMN2 (0.41) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Iodide SCHEMBL1226159 0.96 SMN1; SMN2 (0.41) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Alcohol SCHEMBL2336778 0.94 KMT2A (0.38) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL4344065 0.94 KMT2A (0.50) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL25330776 0.92 KMT2A (0.53) KMT2ASMN1; SMN2MEN1MAPTMAPK1
Hydrochloric Acid SCHEMBL22026959 0.92 KMT2A (0.53) KMT2ASMN1; SMN2MEN1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120136189-A1 BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION CONOCOPHILLIPS COMPANY - IP SERVICES GROUP (US) 2012-05-31 US claimed
WO-2011112514-A1 BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION CONOCOPHILLIPS COMPANY (US) 2011-09-15 WO claimed
US-20110185788-A1 IONIC LIQUIDS AS SOLVENTS IN HEADSPACE GAS CHROMATOGRAPHY KOCH PETER 2011-08-04 US claimed
US-20100239524-A1 MICROPARTICLES PREPARED USING AN IONIC LIQUID NOVARTIS AG (CH) 2010-09-23 US claimed
EP-2144977-A1 LIQUID BIOFUELS CONTAINING DIHYDROXYFURAN, PROPANOL AND ITS PRODUCTION PROCESS FROM POLYOLS ORIGINATED IN AGRICULTURE Correia, Pedro (PT) 2010-01-20 EP claimed
US-7569149-B2 Ionic liquids as solvents in headspace gas chromatography NOVARTIS AG (CH) 2009-08-04 US claimed
WO-2008053284-A1 LIQUID BIOFUELS CONTAINING DIHYDROXYFURAN, PROPANOL AND ITS PRODUCTION PROCESS FROM POLYOLS ORIGINATED IN AGRICULTURE CORREIA PEDRO (PT) 2008-05-08 WO claimed
US-20050205493-A1 Ionic liquids as solvents in headspace gas chromatography NOVARTIS AG (CH) 2005-09-22 US claimed
WO-2000040673-A1 INDUSTRIAL PROCESS AND CATALYSTS THE SECRETARY OF STATE FOR DEFENCE (GB) 2000-07-13 WO claimed
US-5994602-A IN THE PRESENCE OF A HYDROCARBYL ALUMINUM OR GALLIUM HALIDE AND A HYDROCARBYL-SUBSTITUTED IMIDAZOLIUM OR PYRIDINIUM HALIDE BP CHEMICALS LIMITED (GB) 1999-11-30 US claimed
WO-1998047616-A1 CATALYST COMPRISING A BUFFERED IONIC LIQUID AND HYDROCARBON CONVERSION PROCESS, E.G. OLIGOMERISATION BP CHEMICALS LIMITED (GB) 1998-10-29 WO claimed
EP-0693045-B1 ALKYLATION PROCESS BP CHEM INT LTD (GB) 1997-10-22 EP claimed
EP-0791643-A1 Lubricating oils BP Chemicals Limited (GB) 1997-08-27 EP claimed
EP-0693045-A1 ALKYLATION PROCESS BP CHEM INT LTD (GB) 1996-01-24 EP claimed
WO-1995021806-A1 ALKYLATION PROCESS BP CHEMICALS LIMITED (GB) 1995-08-17 WO claimed
EP-3166981-B1 OLIGOSACCHARIDE COMPOSITIONS AND METHODS FOR PRODUCING THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2026-05-13 EP disclosed
US-20260124324-A1 PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS TUFTS COLLEGE (US) 2026-05-07 US disclosed
EP-0693045-A1 ALKYLATION PROCESS BP CHEM INT LTD (GB) 1996-01-24 EP disclosed
WO-1995021806-A1 ALKYLATION PROCESS BP CHEMICALS LIMITED (GB) 1995-08-17 WO disclosed
WO-1995021872-A1 IONIC LIQUIDS BP CHEMICALS LIMITED (GB) 1995-08-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124324-A1 PHOTOCLICK CHEMISTRY OF SILK FOR TEMPORARY UV TATTOOS PTMS, ITK, MATK CHRM2 3100/4885CHRM1 3025/4885ACHE 2133/4885
US-20100239524-A1 MICROPARTICLES PREPARED USING AN IONIC LIQUID FIBP, MIF, CHMP4B CHRM2 2802/4885CHRM1 3005/4885ACHE 3974/4885
US-20120136189-A1 BUFFERED IONIC LIQUIDS FOR OLEFIN DIMERIZATION OSBPL8, OSBP, OSBP2 CHRM2 1943/4885CHRM1 1030/4885ACHE 4012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.