Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616388 | 0.92 | ESR1 (0.44) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL2123530 | 0.83 | HDAC3 (0.38) | CSNK2A2CSNK2A1FABP4FABP5MAPK13 | |
| SCHEMBL2123430 | 0.82 | TNF (0.50) | MGAMGAASIMGAM2CTNNB1 | |
| SCHEMBL21137545 | 0.78 | NOTUM (0.43) | CSNK2A2CSNK2A1FABP4FABP5MAPK13 | |
| SCHEMBL23089731 | 0.75 | MGAM (0.39) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL29814664 | 0.75 | MGAM (0.39) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL2125738 | 0.75 | ESR1 (0.40) | ESR1HDAC3PARP1POLBSMN1; SMN2 | |
| SCHEMBL28922916 | 0.74 | MTNR1A (0.59) | CSNK2A2CSNK2A1ESR1PARP1POLB | |
| SCHEMBL28112933 | 0.74 | NOTUM (0.43) | FABP4FABP5HSD17B10TBXAS1 | |
| SCHEMBL16794890 | 0.73 | MEN1 (0.51) | GAAPOLBKDM4EHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010145201-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-12-23 | — | — | WO | disclosed |