Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463804 | 0.81 | SHBG (0.43) | ALDH1A1EPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL17791666 | 0.81 | ALDH1A1 (0.38) | ALDH1A1EPHX1TP53LMNACYP1A2 | |
| SCHEMBL11240771 | 0.79 | ALDH1A1 (0.37) | ALDH1A1EPHX1TP53LMNACYP1A2 | |
| SCHEMBL4476053 | 0.78 | SHBG (0.40) | ALDH1A1EPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL17791663 | 0.78 | ALDH1A1 (0.35) | ALDH1A1EPHX1 | |
| SCHEMBL28943266 | 0.78 | ALDH1A1 (0.40) | ALDH1A1EPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL17867661 | 0.77 | ALDH1A1 (0.38) | ALDH1A1EPHX1TP53LMNACYP1A2 | |
| SCHEMBL27906535 | 0.73 | EPHX1 (0.43) | ALDH1A1EPHX1TP53MAPTSMN1; SMN2 | |
| SCHEMBL28400955 | 0.73 | EPHX1 (0.43) | ALDH1A1EPHX1TP53MAPTSMN1; SMN2 | |
| SCHEMBL25946700 | 0.72 | ALDH1A1 (0.45) | ALDH1A1EPHX1CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139866-A2 | CRYSTALLINE 1-(CYCLOHEXYLOXYCARBONYLOXY) ETHYL 1-((2'-CYANOBIPHENYL-4-YL)METHYL)-2-ETHOXY-1H-BENZO[D]IMIDAZOLE-7-CARBOXYLATE AND A PROCESS FOR ITS PREPARATION | KRKA, D.D., Novo Mesto (SI) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008129077-A2 | CRYSTALLINE 1-(CYCLOHEXYLOXYCARBONYLOXY) ETHYL 1-((2'-CYANOBIPHENYL-4-YL)METHYL)-2-ETHOXY-1H-BENZO[D]IMIDAZOLE-7-CARBOXYLATE AND A PROCESS FOR ITS PREPARATION | KRKA, D.D. NOVO MESTO (SI) | 2008-10-30 | — | — | WO | disclosed |