Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 11/20 | 0.56 |
| ▸ | FLT3 | P36888 | 5/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5619013 | 0.83 | FLT3 (0.54) | TTKFLT3ADORA3FYNSRC | |
| SCHEMBL3467927 | 0.76 | TTK (0.74) | TTKFLT3 | |
| SCHEMBL9937301 | 0.76 | TTK (0.57) | TTKFLT3ADORA3 | |
| SCHEMBL3469505 | 0.75 | TTK (0.57) | TTKFLT3ADORA3 | |
| SCHEMBL3466151 | 0.75 | TTK (0.62) | TTKFLT3 | |
| SCHEMBL3466904 | 0.74 | TTK (0.69) | TTK | |
| SCHEMBL3469482 | 0.74 | TTK (0.71) | TTKFLT3 | |
| SCHEMBL120443 | 0.74 | KDM4E (0.46) | ADORA3 | |
| SCHEMBL14573301 | 0.73 | FYN (0.47) | TTKADORA3FYN | |
| SCHEMBL8249613 | 0.73 | TTK (0.60) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |