Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28389694 | 0.76 | LMNA (0.35) | LMNATSHR | |
| SCHEMBL25281205 | 0.74 | TSHR (0.59) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL575752 | 0.74 | — | — | |
| SCHEMBL10424109 | 0.73 | POLB (0.39) | TSHRHTT | |
| SCHEMBL2154826 | 0.70 | MEN1 (0.37) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL3469973 | 0.69 | HTT (0.32) | HTT | |
| SCHEMBL3469411 | 0.69 | MEN1 (0.46) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL15873625 | 0.69 | MEN1 (0.41) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL9615247 | 0.67 | TSHR (0.34) | MEN1LMNAHPGDTSHRBLM | |
| SCHEMBL16924894 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405309-B2 | Pyranone derivatives useful for treating cancer | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-07-29 | — | — | US | claimed |
| EP-1720849-B1 | PYRANONE DERIVATIVES USEFUL FOR TREATING CANCER | CENTRE NAT RECH SCIENT (FR) | 2008-05-07 | — | — | EP | claimed |
| US-20070167515-A1 | Pyranone derivatives useful for treating cancer | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2007-07-19 | — | — | US | claimed |
| EP-2237358-B1 | Nonaqueous electrolyte battery | MITSUBISHI CHEM CORP (JP) | 2015-08-12 | — | — | EP | disclosed |
| EP-2128923-B1 | NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY | MITSUBISHI CHEM CORP (JP) | 2013-01-16 | — | — | EP | disclosed |
| EP-2237358-A1 | Nonaqueous electrolyte battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2010-10-06 | — | — | EP | disclosed |
| EP-2128923-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY | Mitsubishi Chemical Corporation (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-7405309-B2 | Pyranone derivatives useful for treating cancer | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-07-29 | — | — | US | disclosed |
| EP-1720849-B1 | PYRANONE DERIVATIVES USEFUL FOR TREATING CANCER | CENTRE NAT RECH SCIENT (FR) | 2008-05-07 | — | — | EP | disclosed |
| US-20070167515-A1 | Pyranone derivatives useful for treating cancer | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2007-07-19 | — | — | US | disclosed |
| EP-1720849-A1 | PYRANONE DERIVATIVES USEFUL FOR TREATING CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) Etablissement Public (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005073211-A1 | PYRANONE DERIVATIVES USEFUL FOR TREATING CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2005-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167515-A1 | Pyranone derivatives useful for treating cancer | HCCS, PDXK, CBR3 | MEN1 1598/4885LMNA 4116/4885HPGD 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.